মঙ্গলবার, ২৯ জানুয়ারী, ২০১৩

Military suicides show signs of spreading in families

Erin Trieb for NBC News

Monica Velez, pictured in Austin, Texas, had two brothers, Jose "Freddy" Velez and Andrew Velez, both of whom served the U.S. military and both are now dead -- Freddy was killed in action in Iraq, and Andrew took his own life.

By Bill Briggs, NBC News contributor

Before Army Spc. Andrew Velez left Texas for the final time, he asked his fragile sister to write him a promise ? a vow he could carry with him to Afghanistan.

Monica Velez knew she owed him that much. In the horrid weeks after each had lost their beloved brother, Freddy Velez, to enemy fire in Iraq, Monica tried to end her life with pills and alcohol. Now, she put pen to paper: ?I will not hurt myself. I will not do anything crazy. I know that Andrew loves me. I know that Freddy loved me.? Andrew folded her note and slipped it into his pocket.

?Don?t break your word to me,? he told her before heading back to war.

Seven months later, Andrew, 22, sat alone in an Army office at a base in Afghanistan. He put a gun to his head and committed suicide. Back in Texas, word reached Monica Velez who, once again, found herself in a dangerous place. Only now, she was alone. Days of alcohol and anti-depressants. Nights of dark thoughts: ?It would just be better if I was gone.?


'The storm' is coming
As the U.S. military suicide rate soared to record heights?during 2012, the families of service members say they, too, are witnessing a silent wave of self-harm occurring within their civilian ranks: spouses, children, parents and siblings.?

Some suicides and suicide attempts ? like those that ravaged the Velez family???are spurred by combat losses.

Others?may be?triggered by exhaustion and despair: As some veterans return debilitated by anxiety, many spouses realize it's now up to them???and will be for decades???to hold the family together.

Specific figures are lacking as no agency tracks civilian suicides within military families.

However, Kristina Kaufmann, a long-time Army wife, knows of three other Army wives, all friends, who took their lives in recent years.

Courtesy Kristina Kaufmann

"When you know that you are the anchor ? and if you go down, the family's going down ? the problem is that you can only do that for so long," said Kristina Kaufmann.

One was Faye Vick, described by Kaufmann as ?the perfect picture of an Army wife???pretty, nice, always with a smile.? Vick and her family lived around the corner from Kaufmann and near Fort Bragg, N.C. In 2006, when Kaufmann?s husband was in Afghanistan and Vick?s husband was deployed overseas, the 39-year-old mother placed herself, her infant and her 2-year-old son in a car inside a closed garage and started the engine, asphyxiating all three with carbon monoxide, according to Kaufmann and to local news reports at the time.

?And I know of too many others through the grapevine,? said Kaufmann, executive director of Code of Support, an Alexandria, Va.-based nonprofit that seeks to bridge the gap between civilians and military America.

?When you know that you are the anchor???and if you go down, the family?s going down???the problem is that you can only do that for so long,? said Kaufmann. ?That population (of spouses) is at the most risk. Because the storm is going to happen when everybody comes home. That?s where we are, unfortunately, going to see an uptick in lots of negative outcomes, including suicide, including suicide among the spouses.?

On Jan. 14, Department of Defense officials acknowledged that during 2012, service members committed suicide at a record pace as more than 349 people took their own lives across the four branches.?The military suicide rate is slightly lower than that of the general public. However, one active-duty member died by suicide every 25 hours last year.?

The Army sustained the heaviest branch toll at 182 suicides, which ??as NBC News reported Jan. 3?? meant that soldier suicides outpaced combat deaths for the first time, according to Pentagon officials.

Defense Secretary Leon Panetta informed Congress last July that American armed forces are in the grip of a suicide "epidemic."?

One of the darkest undercurrents of the glaring statistics is that one suicide in a family boosts future suicide risks for everyone else inside the home.?They can be contagious, say experts like Dr. Barbara Van Dahlen, a psychologist in the Washington, D.C., area and the founder of Give an Hour, which develops networks of mental-health volunteers who respond to both acute and chronic situations.

Numerous researchers have explored the so-called contagion effect of suicides within families and ?there?s no question the data supports there?s at least a doubling of risk,? among surviving family members, said Dr. Alan L. Berman, Ph.D., executive director of the American Association of Suicidology. The organization strives to better understand and prevent suicide.

?It?s understood that risk, in part, is biological,"?Berman said, given that disorders like depression have a genetic component.?

?But it?s also based on social modeling behavior: The suicide of a parent presents a model (for children in that family) of how to deal with problems, and that?s no less true for a spouse.?

Added Van Dahlen: "The closer that family member is to you, the greater risk you?re at. We believe, psychologically, it opens the possibility and ends a taboo."

?The thousands of service members who have killed themselves,? she added, ?they leave in their wake thousands of family members who are now at risk for that same kind of decision."

'I completely lost myself'
The cascade of Velez family tragedies began with pure valor.

On Nov. 13, 2004, Army Cpl. Jose ?Freddy? Velez, 23, sprayed bullets at insurgent forces???covering fire to allow other U.S. soldiers time to retreat from an enemy strong point in Fallujah, Iraq. After his ammo ran dry, Freddy Velez was shot and killed. The Army awarded him the Bronze Star and Silver Star.

Courtesy Monica Velez

"There are days I'm still overwhelmed. And if I sit and think about it, I feel like I wouldn't have to live through all this pain if I just let myself go," said Monica Velez, who shared family photos of brothers Freddy and Andrew.

Andrew, then serving with another unit in Iraq, told Monica of escorting his brother?s body home to Lubbock, Texas ? a job, he said, that required unzipping his brother?s body bag at every stop to re-verify Freddy?s identity.

During the trip, Andrew called his sister repeatedly while en route home and screamed into the phone for nearly two consecutive hours, ?like somebody was killing him,? she said.

?There was nothing I could do,? Monica Velez recalled. ?The operator kept cutting in (to request additional payment for the call) and I just said, ?Add it to my credit card.? He just wailed. That travel home, I think is what eventually broke him.?

Weeks later, Monica broke.

She doesn?t know how close she came to death the first time she tried to end her life. She never was told how slow her pulse became that night. She just remembers regaining consciousness at a hospital in Killeen, Texas???home to Fort Hood, where Freddy was based. She awoke with an IV plugged into her arm. A doctor handed her a list of local psychiatrists then discharged her.

Velez tried, she said, to seek help for her deepening depression but was told that her health insurance would not cover counseling.

Her grief was rooted in a difficult childhood, she said, that forged "tighter than tight" emotional bonds between Velez and her two brothers, turning the siblings into a mutual support group.

?When Freddy passed away, I went through a really hard depression,? she said. ?I went to the emergency room for anxiety attacks. I couldn?t breathe. But nobody knew how to deal with me so they just gave me Ativan (an anti-anxiety drug) and Hydrocodone (a pain killer).

?I started drinking heavily and taking the prescriptions. And one day, I just felt it would be better off if I wasn?t around and decided to take all of the pills. Grief can bring you to that breaking moment.?

Soon after, in February 2005, Andrew sent his older sister (then 25) an email: ?We need to be stronger. We need to protect each other.?

Though he was the youngest of the siblings, Andrew always was ?the strong one,? his sister said. ?But he and Freddy were inseparable.? Near the end of 2005, Andrew told his sister he was redeploying to Afghanistan because, she said, ?I think he felt closer to Freddy there.?

From March through July of 2006, the two swapped calls and emails. In Afghanistan, Andrew grew increasingly despondent, she said, over the unraveling of his marriage and family in Lubbock. He had three children. But he worried, too, about his sister?s state of mind.

?We could both hear it in each other?s voices. He was scared I was going to do something. I was scared he was going to do something.?

He did. Andrew?s suicide on July 25, 2006, drove Monica, at first, into 20-hour workdays at a domestic violence shelter. She wasn?t sleeping or eating. Eventually, she was drinking again, ?from the morning until I passed out,? she said. ?Then, doing it again the next day.

?I completely lost myself. I resigned my job. I stopped paying my bills. I got evicted. I was prescribed anti-depressants. I noticed taking the pills and drinking got me out of the emotions. So I found myself in a dangerous place very quickly.

?Again???several trips to the ER (for overdoses). I?m not sure why I wasn?t ever held there. In my down periods, I would tell myself it would just be better off if I was gone.?

In 2008, a friend at Fort Hood, Texas, connected Velez with the Tragedy Assistance Program For Survivors (TAPS), a resource for anyone who suffers the loss of a military loved one.

?That was the first time anybody had offered to help me with the depression and the grief.? she said.

'Family units breaking down'
Kaufmann, who lost three Army-spouse friends to suicide, argues that military-family suicides should be tracked and researched by the Department of Defense to help mental-health experts begin to slow or stop the problem. She knows, however, such an accounting is not likely.?

?I get the sense that people in the military think that by including families into this kind of discussion ? particularly when you?re talking about the (broader) mental-health impacts on family members ? they look at that as something that will only add to the problem. Whereas, we believe that it would prove to be a solution,? Kauffman said.

?We?ve approached this very myopically. More than half of soldiers are married. Soldiers come with families. And the military has a maddening way of both dismissing families and holding them accountable at the same time. It?s frustrating for us, not only when we?re trying to get our husbands help, but also when you have the family units breaking down,? she added.?

NBC News requested to speak with officials at the newly formed Department of Defense suicide-prevention office about the issue of suicides within military families and whether tracking is needed. A DOD spokeswoman said, however, that the office is only working to address active-duty suicides. The interview request was not granted.

Van Dahlen, meanwhile, believes that asking DOD to track military families is an unreasonable expectation to place on the agency when it already is facing budget cuts.

Even if the DOD wants to ? and many of my colleagues there desperately would want to devote resources to this???those resources are not going to be there,? she said. Rather than putting "the screws to DOD" and doing "even more with even less," Van Dahlen believes public-private partnerships should be encouraged "to figure out how we can (address) this together."

'Like an airborne disease'
More than eight years after Freddy?s combat death, and more than six years removed from Andrew?s suicide, Monica Velez annually runs the Marine Corps Marathon in Washington, D.C., in honor of her fallen brothers.

Matt Slocum / AP file

Monica Velez cleans her brother's name, engraved in a memorial at Fort Hood, Texas.

But, now living in Austin, she acknowledges she still struggles with what she calls, ?those thoughts.?

?There are days I?m still overwhelmed. And if I sit and think about it, I feel like I wouldn?t have to live through all this pain if I just let myself go. It doesn?t just go away. But you learn how to cope. You learn better coping skills,? she said, adding she gained those tools from TAPS.

Army officers at Fort Hood have occasionally asked her, she said, for ideas to help them prevent the rising military suicide rate. She watches that tally, too.

?The numbers take my breath away. I know it can be overwhelming for the Army generals on the other end of the table trying to figure this problem out. Because it?s like an airborne disease going through the building and you?re trying to figure out how to stop it before it gets to you," she said.?

?But it?s coming at a really fast rate, and it?s inevitable.?

Related stories:
Military suicide rate set record high in 2012
The enemy within: Soldier suicides outpace combat deaths in 2012
Some wounded vets shine on 'Alive Day,' others wear black?

Source: http://usnews.nbcnews.com/_news/2013/01/16/16540098-like-an-airborne-disease-concern-grows-about-military-suicides-spreading-within-families?lite

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Patients' own skin cells are transformed into heart cells to create 'disease in a dish'

Patients' own skin cells are transformed into heart cells to create 'disease in a dish'

Monday, January 28, 2013

Most patients with an inherited heart condition known as arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) don't know they have a problem until they're in their early 20s. The lack of symptoms at younger ages makes it very difficult for researchers to study how ARVD/C evolves or to develop treatments. A new stem cell-based technology created by 2012 Nobel Prize winner Shinya Yamanaka, M.D., Ph.D., helps solve this problem. With this technology, researchers can generate heart muscle cells from a patient's own skin cells. However, these newly made heart cells are mostly immature. That raises questions about whether or not they can be used to mimic a disease that occurs in adulthood. In a paper published January 27 in Nature, researchers at Sanford-Burnham Medical Research Institute and Johns Hopkins University unveil the first maturation-based "disease in a dish" model for ARVD/C. The model was created using Yamanaka's technology and a new method to mimic maturity by making the cells' metabolism more like that in adult hearts. For that reason, this model is likely more relevant to human ARVD/C than other models and therefore better suited for studying the disease and testing new treatments.

"It's tough to demonstrate that a disease-in-a-dish model is clinically relevant for an adult-onset disease. But we made a key finding here?we can recapitulate the defects in this disease only when we induce adult-like metabolism. This is an important breakthrough considering that ARVD/C symptoms usually don't arise until young adulthood. Yet the stem cells we're working with are embryonic in nature," said Huei-Sheng Vincent Chen, M.D., Ph.D., associate professor at Sanford-Burnham and senior author of the study.

To establish this model, Chen teamed up with expert ARVD/C cardiologists Daniel Judge, M.D., Joseph Marine, M.D., and Hugh Calkins, M.D., at Johns Hopkins University. Johns Hopkins is home to one of the largest ARVD/C patient registries in the world.

"There is currently no treatment to prevent progression of ARVD/C, a rare disorder that preferentially affects athletes. With this new model, we hope we are now on a path to develop better therapies for this life-threatening disease," said Judge, associate professor and medical director of the Center for Inherited Heart Disease at the Johns Hopkins University School of Medicine.

Disease in a dish

To recreate a person's own unique ARVD/C in the lab, the team first obtained skin samples from ARVD/C patients with certain mutations believed to be involved in the disease. Next they performed Yamanaka's technique: adding a few molecules that dial back the developmental clock on these adult skin cells, producing embryonic-like induced pluripotent stem cells (iPSCs). The researchers then coaxed the iPSCs into producing an unlimited supply of patient-specific heart muscle cells. These heart cells were largely embryonic in nature, but carried along the original patient's genetic mutations.

However, for nearly a year, no matter what they tried, the team couldn't get their ARVD/C heart muscle cells to show any signs of the disease. Without actual signs of adult-onset ARVD/C, these young, patient-specific heart muscle cells were no use for studying the disease or testing new therapeutic drugs.

Speeding up time

Eventually, the team experienced the big "aha!" moment they'd been looking for. They discovered that metabolic maturity is the key to inducing signs of ARVD/C, an adult disease, in their embryonic-like cells. Human fetal heart muscle cells use glucose (sugar) as their primary source of energy. In contrast, adult heart muscle cells prefer using fat for energy production. So Chen's team applied several cocktails to trigger this shift to adult metabolism in their model.

After more trial and error, they discovered that metabolic malfunction is at the core of ARVD/C disease. Moreover, Chen's team tracked down the final piece of puzzle to make patient-specific heart muscle cells behave like sick ARVD/C hearts: the abnormal over-activation of a protein called PPAR?. Scientists previously attributed ARVD/C to a problem in weakened connections between heart muscle cells, which occur only in half of the ARVD/C patients. With the newly established model, they not only replicated this adult-onset disease in a dish, but also presented new potential drug targets for treating ARVD/C.

What's next?

Chen's team was recently awarded a new grant from the California Institute for Regenerative Medicine to create additional iPSC-based ARVD/C models. With more ARVD/C models, they will determine whether or not all (or at least most) patients develop the disease via the same metabolic defects discovered in this current study.

Together with the Johns Hopkins team, Chen also hopes to conduct preclinical studies to find a new therapy for this deadly heart condition.

###

Sanford-Burnham Medical Research Institute: http://www.burnham-inst.org

Thanks to Sanford-Burnham Medical Research Institute for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

This press release has been viewed 39 time(s).

Source: http://www.labspaces.net/126483/Patients__own_skin_cells_are_transformed_into_heart_cells__to_create__disease_in_a_dish_

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Study shows potential of differentiated iPS cells in cell therapy without immune rejection

Study shows potential of differentiated iPS cells in cell therapy without immune rejection

Monday, January 28, 2013

A new study from Boston University School of Medicine (BUSM) shows that tissues derived from induced pluripotent stem (iPS) cells in an experimental model were not rejected when transplanted back into genetically identical recipients. The study, published online in Cell Stem Cell, demonstrates the potential of utilizing iPS cells to develop cell types that could offer treatment for a wide range of conditions, including diabetes, liver and lung diseases, without the barrier of immune rejection.

Ashleigh Boyd, DPhil, and Neil Rodrigues, DPhil, the study's senior authors, are assistant professors of dermatology at BUSM and researchers at the Center for Regenerative Medicine (CReM) at Boston University and Boston Medical Center (BMC). They also are lead investigators at the National Institutes of Health's Center of Biomedical Research Excellence (COBRE) at Roger Williams Medical Center, a clinical and research affiliate of BUSM.

iPS cells can be developed from adult cell types, such as skin or blood, by returning them to a stem cell state using genetic manipulation. iPS cells are capable of maturing (differentiating) into all the specific cell types in the body, making them a powerful tool for biological research and a source of tissues for transplantation based therapies. Given that iPS cells can be made in a patient-specific manner, there should be great potential for them to be transplanted back into the same patient without rejection. Yet a study published in Nature in 2011 demonstrated that iPS cells transplanted in the stem cell state were rejected in genetically identical recipients.

"The Nature study provocatively suggested that tissues derived from patient-specific iPS cells may be immunogenic after transplantation. However, it never directly assessed the immunogenicity of the therapeutically relevant cell types that could be utilized in regenerative medicine and transplantation," said Rodrigues.

The BUSM researchers evaluated this matter by taking adult cells from an experimental model and deriving iPS cells from them. They then differentiated the iPS cells into three cell types: neuronal (nerve); hepatocytes (liver); and endothelial (blood vessel lining) cells. These three cell types represent each of the three germ layers present during embryonic development ? mesoderm, ectoderm and endoderm. Cells from these layers differentiate and ultimately develop into the body's tissue and organ systems. Using experiments to mirror the potential clinical use of patient-specific iPS cells in cell therapy, the team transplanted each of the differentiated cells into a genetically identical experimental model and found no signs of an elevated immune response or indications of rejection.

The study results suggest that using patient-specific iPS cells should overcome issues of immune rejection in transplantation, which will be a significant problem for potential embryonic stem cell-derived therapies. Immune rejection in transplantation is treated clinically by immunosuppressive drugs but they can have serious side-effects, including the risk of developing cancer.

"If the use of immunosuppressive drugs can be avoided, as may be the case for patient-specific iPS cell based therapies, it would be preferable. Our results are very promising and future work should be directed at assessing whether tissues derived from human iPS cells will similarly lack immunogenicity," said Boyd.

###

Boston University Medical Center: http://www.bmc.org

Thanks to Boston University Medical Center for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

This press release has been viewed 34 time(s).

Source: http://www.labspaces.net/126481/Study_shows_potential_of_differentiated_iPS_cells_in_cell_therapy_without_immune_rejection

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সোমবার, ২৮ জানুয়ারী, ২০১৩

Michigan moves to No. 1 in AP poll

Michigan is No. 1 in The Associated Press' college basketball poll for the first time since its Fab Five days 20 years ago.

For the second straight week the No. 1 team lost. This time it was Duke, which was routed 90-63 by Miami in the third-worst defeat by a top-ranked team.

Michigan received 51 first-place votes from the 65-member national media panel Monday. Kansas moved up one spot to No. 2 and had 13 first-place votes. They are the only one-loss teams in the poll. Indiana, Florida, which drew the other first-place vote, and Duke complete the top five.

The Wolverines advanced from No. 2 to become No. 1 for the fourth time. They were at the top for 10 weeks in 1964-65, eight weeks in 1976-77 and three weeks at the start of 1992-93, the Fab Five's second season together.

That season, Chris Webber, Juwan Howard, Jalen Rose, Jimmy King and Ray Jackson made it to the national championship game for the second straight year.

Michigan is the second Big Ten team to be No. 1 this season. Indiana was the preseason No. 1 and stayed there for the first five weeks of the regular season. Duke moved in for four weeks before Louisville and the Blue Devils both held it for one week.

Rounding out the top 10 are No. 6 Syracuse, followed by Gonzaga, Arizona, Butler and Oregon. Miami rode its win over Duke to a 13-place jump in the poll, from 25th to 14th.

Fourteen ranked teams, including half the top 10, lost at least one game last week. Four teams, including Louisville, which dropped from fifth to 12th, lost twice last week.

San Diego State and Marquette returned to the rankings this week, replacing Virginia Commonwealth, which was 19th, and Notre Dame, which was 24th.

Source: http://news.yahoo.com/michigan-moves-no-1-ap-poll-190958335--spt.html

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Relocation Sales Manager - InsuranceSalesWeb.com


Sales manager is a corporate salesperson in charge of building a book of business within an assigned territory designation. The position involves selling a portfolio of products and services to meet the needs of business travelers, expatriates and foreign nationals. Channels for sales development include corporate accounts, large relocation and travel groups, airlines, insurance brokers, banks and affinity groups. The sales manager must be flexible and experienced with a variety of skills including direct and business-to-business sales, account management, new business development and third party account management. He/she will acquire clients for our company by developing corporate or group prospects.

The position requires account management skills. He/she will be responsible for managing and expanding our existing and prospective client base. The sales manager will need to ensure the accuracy of regional files and the database of accounts in his/her respective territory. He/she will also be responsible for coordinating back office logistics. The sales manager is responsible for soliciting business by sending out company collateral, responding to inquiries, going on sales calls, developing and negotiating contracts, running reports and developing proposals.

Position Requirements
Position requires 3 to 5 years previous sales experience and a combination of excellent oral and written communication skills. Previous global mobility industry or insurance industry experience preferred. The candidate must have good people skills, patience and flexibility. He/she must be responsible, persuasive, confident and reflect well upon our business. The position calls for the ability to work creatively, independently and manage detail. Computer literacy is required along with knowledge of word processing, PowerPoint, Excel and database software.

Bachelor?s degree or equivalent sales experience
Multilingual abilities are a plus.

About Us
Chartis is a world leading property-casualty and general insurance organization serving more than 40 million clients in over 160 countries and jurisdictions. With a 90-year history, one of the industry's most extensive ranges of products and services, deep claims expertise and excellent financial strength, Chartis enables its commercial and personal insurance clients alike to manage virtually any risk with confidence. For additional information, please visit our website at http://www.Chartisinsurance.com.

At Chartis we support and encourage a diverse work environment. EOE.

Requisition #: 81371

Source: http://jobs.insurancesalesweb.com/c/job.cfm?site_id=1636&jb=12108392

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Anger Management and Modifying Your Daily Behavior | Healthy ...

Webmaster | January 27, 2013 (10 hours ago) | no comments



Anger Management and Modifying Your Daily BehaviorAnger management is a strategy by which a human being comes to discover how their anger is brought on.

Sometimes conflicts in critiques, insecurity, or emotions of unfair treatment could lead to these issues.

Many modern day beliefs with regard to anger management lean toward the premise of living in the moment.

Once we?realize?that we in reality have very little or no power over other people?s thoughts and ideas, we can start to liberate ourselves and take responsibly for our own anger management triggers.

Occasionally in the course of a dispute folks will come to feel that another person?s opinion is a immediate attack on the very moral?fiber?of an individual. All of us is entitled to their own attitude and opinion.. Other people?s. You may wonder why this can make us angry.

The major mistake that people make whenever they process ridicule is that they believe the criticism to be a personal attack and thus they tend to take it personally. An effective anger management technique lies in seeing criticism constructively.

For instance, your spouse might complain that they don?t receive enough attention from you. Rather than pondering it as a personal attack, a very good anger management method will focus on this conduct specifically and not be offended by a personal attack.

By removing ourselves emotionally from criticism, we can commence to cultivate an perspective toward change that is balanced and can lead to less episodes of inappropriate anger. We have developed the process sound far too effortless, understandably.

But the truth of the matter is, it is challenging to alter. ?No pain, no gain? is a basic term that can come to mind in relation to anger management. It is so straightforward to return to old?behavior? specifically when we believe another person is attacking us personally. At this stage you really should seek out professional support with your anger troubles.

All through my tenure as a psychologist, many individuals who wanted advice in dealing with melancholy and anxiety. the underlining sense was anger. To understand the root of the condition, it could also require a variety of classes. We can start working together the moment the complaint with the customer is acknowledged as one of anger management

Mastering anger management skills has assisted countless people take notice of an improvement in overall amounts of fear and depression after only a couple of sessions.

Collectively with depression, fear, and a great number of other stressors that can take place in the path of everyday, typical daily life, anger must be harnessed to make full use of your intellect and refine it to the greatest of its healthy capacity.

A number of alternate concepts around psychological health complications, for example anger management concentrate highly on methods such as meditation and self-awareness therapy. These actions can give you power over your ideas as well as tranquility of mind, specifically feelings of rage and anger.

Anger by itself is not a negative thing, it is important to note this at this point. Quite a few of the accomplishments or overcoming of factors in history have at some point been motivated by anger.

The appropriate utilization of anger has the capacity to be an extremely potent foundation of energy.

All through history, anger has been accountable for bringing about incredible changes in the world and the way that we are living.

For more information, get in touch with an anger management therapist in your area.

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Article by Wilmer Charpia

About the Author :?Wilmer Charpia is a personal trainer in Brisbane with over 10-years experience in personal training!

www.healthylifestyleplus.com

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Tags: Anger, Anger management, Behaviors., Every, Healthy Lifestyle Plus, Management, Modifying, www.healthylifestyleplus.com

Category: Healthy Mind

Source: http://www.healthylifestyleplus.com/mind/anger-management-and-modifying-the-every-day-behaviors/

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AJay Parham ? How Motivational Speakers Aid In Self Improvement

Motivational speakers are people who are appropriately trained to handle an audience with a particular goal at heart, and that is to supply motivation for different conditions that occur throughout the normal span of li?

We all reach the point in life where it appears like something is missing, something small that could help you get to the point in your life where you could attain true pleasure, whether it maintain the region of function, family, relationships, or anything else.

Inspirational speakers are people who are professionally trained to address an audience with a specific goal at heart, and that is to supply motivation for different situations that occur throughout the natural span of life. Perhaps you should consider attending a class or finding out about events that feature motivational speakers in your neighborhood area, if you desire a little determination in virtually any area of your existence.

It is okay to need a tiny bit of help sometimes; inspirational speakers are excellent aids in home development while they design their messages and organize their terms you might say that is supposed to engage the listener, and allow the listener set themselves in the speaker?s position allowing both of these to identify with each other. This way, it is easier for the listener to see the way out of these present problem, to see how to fix the problem or correct whatever it is concerning the situation that?s not right. It is often something small and minute that stops people in life, and home development is often a of finding what it?s that has to be fixed, number matter the size or severity of the problem.

A few of the areas by which motivational speakers can certainly help in self improvement are:

*Parenting

- Step Parenting

*Careers

- Transitioning Careers

- Changing Careers

- Career Advancement
networking
*Relationships

- Marriage

*And More!

For each of life?s circumstances, there is a minumum of one motivational speaker out there who is trained to deal in that; a variety of people choose to attend motivational speaker events, whether it is for work or pleasure. You mightn?t think that motivational speakers and activities like that are not your cup of tea, but if you try attending a minumum of one event, chances are that your mind can change. True, inspirational speakers aren?t for anyone. Their model is to inspire and stimulate the brain and no person is in to that. Nevertheless, if you?re at all into self improvement and you?re looking to make a change in your life, consider taking the advice of a speaker, or at least being open to the theory. You could be surprised with the results!

Source: http://ajayparham.com/blog/2013/01/27/how-motivational-speakers-aid-in-self-improvement/

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রবিবার, ২৭ জানুয়ারী, ২০১৩

Clarksville Parks and Recreation Report for January 27th, 2013 ...

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Clarksville Parks and RecreationClarksville, TN ? The weekly Clarksville Parks and Recreation Department Recreation Report provides Clarksvillians with a glimpse at the activities and events that are available from the Parks and Recreation Department for them to enjoy together as a family.

This weeks highlights include:

  • Nominate a Coach TODAY!
  • Youth Recreation Leagues ? Baseball, Blastball?, Softball and T-ball
  • Indoor Aquatic Center to host event just for toddlers
  • Surrender of Clarksville

Nominate a Coach TODAY!

Clarksville Sports Legends AwardsNominations are now being accepted for the 3rd Annual Clarksville Sports Legends Awards. The City of Clarksville Parks and Recreation Department will once again honor both current and past coaches who are or have made a unique difference and solid contribution to sports and athletics in the Clarksville-Montgomery County area.

Winning coaches will be honored at the 2012 Legends Award Dinner which will be held February 28th, 2013, beginning at 6:30pm at the Wilma Rudolph Event Center. Coaches that are currently coaching or coached in 2012 are invited to attend this free event.

A ticket is required to attend and can be reserved at the City of Clarksville Parks and Recreation main office or online at www.cityofclarksville.com/legends. Because of space limitations, there are only 200 tickets available. Last day to pick up a ticket is February 22nd.

Nomination forms are available to pick up at the Clarksville Parks and Recreation Main Office, downloaded or completed online at www.cityofclarksville.com/legends. All nomination forms must be received by 4:30pm, February 1st.

Youth Recreation Leagues

Baseball, Blastball?, Softball and T-ball

BlastballYou can register your child at any of our community centers or at the Main office beginning February 6th through March 30th for our Youth Recreation Leagues. The baseball, softball, and t-ball league is open to youth ages 5 to 12.

Your child?s birth certificate is required at registration. All games are played at Heritage Park Baseball Fields.

The cost to play in any of the youth recreation leagues is $40.00 per child and includes team shirt, hat and medal.

Once again, for the 3 to 4 year olds, we will be offering Blastball?. This fun alternative to traditional t-ball uses a ?honking? base to entertain younger players- adding excitement to the game. It concentrates on developing a child?s running, hitting, catching, fielding, and throwing skills.

Indoor Aquatic Center to host event just for toddlers

Indoor Aquatic Center - New ProvidenceThe Indoor Aquatic Center, located at 166 Cunningham Lane, is excited to host the first-ever Toddler Splash on February 6th. Kids, ages 1 to 5-years-old, can enjoy fun such as a water parade, penny hunt, water games, crafts and even a ?fishing pond.?

The event is open to children ages 1-5 from 10:00am to 2:00pm. Cost to attend is $3.00 per person, including adults. A parent or adult guardian must accompany toddlers in the water.

Pre-registration is available at recpro.cityofclarksville.com and is strongly encouraged.

Surrender of Clarksville

Fort Defiance Interpretive CenterThe Fort Defiance Interpretive Center, located at 120 Duncan Street, will host a living history weekend to commemorate the 151st anniversary of the Surrender of Clarksville, Saturday, February 16th from 10:00am to 4:00pm and Sunday, February 17th from 1:00pm to 4:00pm.

Come see uniformed Civil War re-enactors from the 50th Tennessee Reenactment Group who will provide living history and musket firing demonstrations. Musket firing demonstrations will take place at 11:00am and 2:00pm on Saturday, and 1:00pm and 3:00pm on Sunday. Visitors can also tour the permanent exhibit which includes the 18-minute film, ?Crossroads of Change 1861-1865?.

This two-day event is free and open to the public. Visit www.fortdefianceclarksville.com for more information.

Filed Under Community
Topics: Birth Certificate, Blastball, civil war, Clarksville Parks and Recreation Department, Clarksville Sports Legends Awards, Clarksville TN, Clarksville-Montgomery County Area, Crossroads of Change, Cunningham Lane, Duncan Street, Fort Defiance Civil War Park and Interpretive Center, Fort Defiance Interpretive Center, Heritage Park, Heritage Park Baseball Fields, Indoor Aquatic Center, Legends Award Dinner, Reenactors, Registration, Surrender of Clarksville, Toddler Splash, Wilma Rudolph Event Center, Youth Baseball Leagues, Youth Blastball League, Youth Softball Leagues, Youth T-Ball League

Source: http://www.discoverclarksville.com/articles/2013/01/27/clarksville-parks-and-recreation-report-for-january-27th-2013/

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It's Official: Disney Confirms That JJ Abrams Will Direct the Next Star Wars Episode VII

It's official guys. Disney has just confirmed that the next Star Wars: Episode VII will be directed by JJ Abrams. Yep, the guy in charge of Star Trek is officially in charge of Star Wars. More »


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Video: Tina Turner may become Swiss citizen

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Beyonce on Lip-Synching Scandal: Can I Live?!?

Source: http://www.thehollywoodgossip.com/2013/01/beyonce-on-lip-synching-scandal-can-i-live/

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Teargas and protests mark second anniversary of Egypt uprising

CAIRO (Reuters) - Hundreds of youths fought Egyptian police in Cairo on Friday on the second anniversary of the revolt that toppled Hosni Mubarak and brought the election of an Islamist president who protesters accuse of riding roughshod over the new democracy.

The January 25 anniversary showcased the divide between the Islamists and secular foes hindering President Mohamed Mursi's efforts to get a stagnant economy moving, and reverse a plunge in Egypt's currency, by attracting back investors and tourists.

Inspired by Tunisia's ground-breaking popular uprising, Egypt's revolution spurred further revolts across the Arab world. But the sense of common purpose that united Egyptians two years ago has given way to internal strife that has only worsened and last month triggered lethal street battles.

Opponents of Mursi and his Muslim Brotherhood allies began massing in Cairo's Tahrir Square to revive the demands of a revolution they say has been betrayed by Islamists.

Police battled hardcore protesters who threw petrol bombs and firecrackers as they tried to approach a wall blocking access to government buildings near the square in the early hours of the morning.

Clouds of tear gas fired by police filled the air. At one point, riot police used one of the incendiaries thrown at them to set ablaze at least two tents erected by the youths, a Reuters witness said. Clashes between stone-throwing youths and the police continued in streets near the square into the day.

Ambulances ferried away a steady stream of casualties. The health ministry said 25 people had been injured since Thursday in clashes around Tahrir Square.

Some protesters pledged to march to Mursi's palace.

Thousands more protested against the Brotherhood in cities across Egypt including Suez, Ismailia, Port Said and Alexandria.

The Brotherhood decided against mobilizing in the street for the anniversary, wary of the scope for more conflict after violence in December that was fuelled by Mursi's campaign to fast-track an Islamist-tinged constitution.

"The people want to bring down the regime," declared banners in the square, echoing the main Arab Spring slogan of 2011. "Save Egypt from the rule of the Supreme Guide," said another, a reference to leader of the Muslim Brotherhood, Mohamed Badie.

Mursi, in a speech on Thursday marking the Prophet Mohammad's birthday, called on Egyptians to mark the anniversary "in a civilized, peaceful way that safeguards our nation, our institutions, our lives".

"The Brotherhood is very concerned about escalation, that's why they have tried to dial down their role on January 25," said Shadi Hamid director of research at the Brookings Doha Center.

"There may very well be the kinds of clashes that we've seen before, but I don't see anything major happening that is going to fundamentally change the political situation," he said.

BADIE CALLS FOR "PRACTICAL, SERIOUS COMPETITION"

With its eye firmly on forthcoming parliamentary elections, the Brotherhood marked the anniversary with a big charity drive across the nation. It plans to deliver medical aid to 1 million people and distribute affordable basic foodstuffs.

Writing in Al-Ahram, Egypt's flagship state-run daily, Brotherhood leader Badie said the country was in need of "practical, serious competition" to reform the corrupt state left by the Mubarak era.

"The differences of opinion and vision that Egypt is passing through is a characteristic at the core of transitions from dictatorship to democracy, and clearly expresses the variety of Egyptian culture," he wrote.

Still, Mursi faces discontent on multiple fronts.

His opponents say he and his group are seeking to dominate the post-Mubarak order. They accuse him of showing some of the autocratic impulses of the deposed leader by, for example, driving through the new constitution last month.

"I am taking part in today's marches to reject the warped constitution, the 'Brotherhoodisation' of the state, the attack on the rule of law, and the disregard of the president and his government for the demands for social justice," Amr Hamzawy, a prominent liberal politician, wrote on his Twitter feed.

The Brotherhood dismisses many of the criticisms as unfair. It accuses its opponents of failing to respect the rules of the new democracy that put the Islamists in the driving seat by winning free elections.

Six months into office, Mursi is also being held responsible for an economic crisis caused by two years of turmoil. The Egyptian pound has sunk to record lows against the dollar.

SOURCES OF FRICTION ABOUND

Other sources of friction abound. Little has been done to reform brutal Mubarak-era security agencies. A spate of transport disasters on roads and railways neglected for years is feeding discontent as well. Activists are impatient for justice for the victims of violence over the last two years.

These include hardcore soccer fans, or ultras, who have been rallying in recent days to press for justice for 74 people killed in a soccer stadium disaster a year ago in Port Said after a match between local side al-Masry and Cairo's Al Ahly.

A verdict in the case brought against 73 people charged in connection with the deaths had been expected on Saturday, but could be delayed after a request by the prosecutor for time to present new evidence. A delay will likely kindle more protests.

The parties that called for Friday's protests listed demands including a complete overhaul of the constitution.

Critics say the constitution, which was approved in a referendum, offers inadequate protection for human rights, grants the president too many privileges and fails to curb the power of a military establishment supreme in the Mubarak era.

Mursi's supporters say enacting the constitution quickly was crucial to restoring stability desperately needed for economic recovery, and that the opposition is making the situation worse by perpetuating unrest.

(Additional reporting by Ashraf Fahim; Writing by Tom Perry; Editing by Mark Heinrich)

Source: http://news.yahoo.com/egyptian-opposition-mark-uprising-protests-012625590.html

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Oregon City fire displaces one resident, two pets | OregonLive.com

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Researchers discover new mutations driving malignant melanoma

Friday, January 25, 2013

Two new mutations that collectively occur in 71 percent of malignant melanoma tumors have been discovered in what scientists call the "dark matter" of the cancer genome, where cancer-related mutations haven't been previously found.

Reporting their findings in the Jan. 24 issue of Science Express, the researchers from Dana-Farber Cancer Institute and the Broad Institute said the highly "recurrent" mutations ? occurring in the tumors of many people ? may be the most common mutations in melanoma cells found to date.

The researchers said these cancer-associated mutations are the first to be discovered in the vast regions of DNA in cancer cells that do not contain genetic instructions for making proteins. The mutations are located in non-protein-coding DNA that regulates the activity of genes.

This non-coding DNA, much of which was previously dismissed as "junk," accounts for 99 percent of a cell's genome. A large number of oncogenic mutations in cancer have been identified in the past several decades, but all have been found within the actual genetic blueprints for proteins.

"This new finding represents an initial foray into the 'dark matter' of the cancer genome," said Levi Garraway, MD, PhD, of Dana-Farber and the Broad and the article's senior author.

"In addition, this represents the discovery of two of the most prevalent melanoma gene mutations. Considered as a whole, these two TERT promoter mutations are even more common than BRAF mutations in melanoma. Altogether, this discovery could cause us to think more creatively about the possible benefits of targeting TERT in cancer treatment or prevention."

The mutations affect a promoter region ? a stretch of DNA code that regulates the expression of a gene ? adjacent to the TERT gene. TERT contains the recipe for making telomerase reverse transcriptase, an enzyme that can make cells virtually immortal, and is often found overexpressed in cancer cells. A promoter region of DNA controls the rate of a gene's transcription ? the copying of its DNA recipe into a message used by the cell to manufacture a protein.

"We think these mutations in the promoter region are potentially one way the TERT gene can be activated," said Franklin Huang, MD, PhD, co-first author of the report along with Harvard MD-PhD student Eran Hodis, of Dana-Farber and the Broad Institute.

To investigate the mutation's effect, the researchers hooked the mutant TERT promoter to a gene that makes luciferase ? a light-emitting protein. They observed that the mutant promoter increased the production of luciferase in laboratory cell lines. In the same way, the scientists presume, the mutant promoter in human pigmented skin cells can send the TERT gene into overdrive, potentially contributing to the development of melanoma.

The mutations were discovered when the scientists sifted through data from whole-genome sequencing of malignant melanoma tumors. Unlike "whole-exome" searches that examine only the protein-coding DNA of a cell's genome, whole-genome searches scan all of the DNA, including the non-coding regions.

In analyzing whole-genome data, the investigators discovered the two somatic, or not-inherited, mutations in 17 of 19 (89 percent) of the tumors. Next, they sequenced a larger number of melanoma tumors and found that the two mutations were present in 71 percent of tumors in total.

The researchers said the same mutations are present in cell lines from some other malignancies, and that preliminary evidence showed they might be unusually common in bladder and liver cancers. They also noted that the discovery of these important mutations in DNA previously not linked to cancer-causing alterations highlights the value of whole-genome searches of tumor DNA.

###

Dana-Farber Cancer Institute: http://www.dfci.harvard.edu

Thanks to Dana-Farber Cancer Institute for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

This press release has been viewed 13 time(s).

Source: http://www.labspaces.net/126468/Researchers_discover_new_mutations_driving_malignant_melanoma_

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UN Kuwait invasion fund pays out $1.3 billion

(AP) ? The U.N. panel that settles claims for damages from victims of Iraq's 1990 invasion of Kuwait has paid out another $1.3 billion ? bringing the total so far to $40.1 billion.

The U.N. Compensation Commission did not disclose the identities of the claimants on Thursday but said the money goes toward settling two claims for damages to Kuwait's oil fields, as well as production and sales losses.

The Geneva-based commission was established by the U.N. Security Council in 1991 and is funded by a 5 percent tax on the export of Iraqi oil.

It has approved $52.4 billion in total compensation to more than 100 governments and international organizations, and makes payments every three months.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/cae69a7523db45408eeb2b3a98c0c9c5/Article_2013-01-24-UN-Iraq-Compensation/id-5cab615aeca04f849694ec9e5bde6d78

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Quotations of the day

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Please try Yahoo Help Central if you need more assistance.

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Why your business should start using video online conferencing ...

Talking to any clients, potential new customers and investors is always important. At all costs, you?ll probably want to maintain a regular dialogue with them, but did you ever consider the price you?re paying for talking to them? You might not realise it, but it?s possible to save your business money while making communication easier with the help of web conference services offered by Powwownow. It could make a huge difference to your company and the way it works, saving money and time in the process.

In terms of money saving, conference calling via audio and/or video can really help to cut down the cost of communications. How it does so is eliminate the need to travel long distances and spend a small fortune on fuel or tickets to get to a meeting point. Organising a conference call in place of a traditional meeting will save your business plenty of money, and doing so several times over could mean the difference between just breaking even and making a sizeable profit depending on the size of your business.

videoconferencing

Web conferencing can also be a real time saver. As well as saving money on trips to meetings that could cost hundreds at a time, using web conferencing to communicate with important people can save time that would have otherwise been spent travelling. The time saves could be spent on other aspects on the business such as accounting, paperwork or even on arranging extra conference calls which may help to get you additional clients and therefore increase your income, which is great if you think about it.

Ease of communication is another reason to consider using video conferencing. You can invite people from all over the world to any conference call, which makes it preferable to a normal phone call. You can get your point across in a clear manner and even use visual aids during a video conference call too. Aside from that, there?s also the opportunity to collaborate with employees in different parts of the office, not to mention anyone who works from home or another remote location, which makes it a must-have tool for anyone who wants to communicate easily and efficiently.

GUEST BLOG: This helpful small business advice was provided by the web conference experts at Powwownow.

Source: http://sme-blog.com/guest-blog/why-your-business-should-start-using-video-online-conferencing?utm_source=rss&utm_medium=rss&utm_campaign=why-your-business-should-start-using-video-online-conferencing

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One Hour Air Conditioning & Heating New Port Richey Reaffirm their ...

Air condition and heating experts One Hour Air Conditioning & Heating continue their impressive tradition of winning business awards. The company has just been chosen by Angie's List for their 2012 Super Service Award.

Tarpon Springs, FL (PRWEB) January 24, 2013 -?One Hour Air Conditioning & Heating's award winning streak continues with yet another prestigious business award for the family operated heating & air conditioning New Port Richey service operators. Official sources have just informed that One Hour Air Conditioning & Heating is one of the proud recipients of the 2012 Angie?s List Super Service Award. This award is extremely sought after in the service industry and is awarded every year to approximately 5 percent of all the companies rated on Angie?s List.

It may be recalled that the Florida based company was recently crowned as the 'Business of the Year 2012' by the Tarpon Springs Chamber of Commerce. The NPS system has ranked them third amongst over 160 One Hour franchises throughout the entire United States and Canada, in terms of their customer service. Exemplary customer focus and thriving business practices have made One Hour Air Conditioning & Heating the most preferred heating and air conditioning service provider in Tarpon Springs and adjoining areas.

This top rated family operated business was founded in the year 2009 by Kim O'Kelley, father Ed O'Kelley and brother Corey O'Kelley. Unlike many other air conditioning New Port Richey companies, all the staffs of One Hour Air Conditioning & Heating are background checked and drug tested before hiring. The range of guarantee offered by the company is unmatched in the industry. Their service is available 24/7/365 and no extra charges apply for work done during the night, weekends, or holidays.

About One Hour Air Conditioning & Heating

One Hour Air Conditioning & Heating is an air conditioning and heating services experts serving New Port Richey, Tarpon Springs and adjoining regions. The company has just won the 2012 Super Service Award by Angie's List.

About Angie's List

Angie?s List helps consumers have happy transactions with local service professionals in more than 550 categories of service, ranging from home improvement to health care. More than 1.5 million paid households use Angie?s List to gain unlimited access to local ratings, exclusive discounts, the Angie?s List magazine, and the Angie?s List complaint resolution service.

Contacts:

One Hour Air Conditioning & Heating
1820 S. Pinellas Ave. #108
Tarpon Springs, FL 34689
(727) 916-7910
http://www.onehourairwestpasco.com/

Kim O'Kelley
One Hour Air Conditioning & Heating
http://www.onehourairwestpasco.com/
(727) 916-7910

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Source: http://www.franchising.com/news/20130124_one_hour_air_conditioning_amp_heating_new_port_ric.html

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FAA: No timetable to return Boeing 787s to skies

5 hrs.

TOKYO/WASHINGTON - Japanese regulators have joined their U.S. counterparts in all but ruling out overcharged batteries as the cause of recent fires on the Boeing Co 787 Dreamliner, which has been grounded for a week with no end in sight.

Solving the battery issue has become the primary focus of the investigation, though the head of the U.S. Federal Aviation Administration said on Wednesday there are still no firm answers as to the cause and no clear timetable yet for returning the plane to flight.

Meanwhile, as deliveries of the cutting-edge passenger jet back up, a key Chinese customer lamented the delays and said its growth plans were being hampered by its inability to get the planes on time.

Regulators grounded the Dreamliner on Jan. 16 after a series of safety incidents, including battery fires on planes in the United States and Japan. The Japanese incident forced a plane to make an emergency landing.

Last weekend the U.S. National Transportation Safety Board said the fire on a Japan Airlines Co Ltd 787 in Boston was not due to excess voltage, and on Wednesday, Japanese officials all but ruled it out for the incident on an All Nippon Airways Co Ltd plane there.

"On the surface, it appears there was no overcharging," said Norihiro Goto, chairman of the Japan Transport Safety Board, at a media briefing.

"The fact that such electrical system-related incidents would occur consecutively, purely from my perspective, could not have been expected. We are finding it difficult trying to figure out what kind of investigative stance we should take."

Late Wednesday, the NTSB said more tests are underway on the battery damaged in the Boston fire, including CT scans of the individual cells. The board's chairman, Deborah Hersman, is due to provide a fuller update Thursday.

The investigation has also renewed scrutiny on the FAA's 2007 decision to let Boeing use a highly flammable battery technology on the 787. A U.S. Senate committee will hold a hearing in coming weeks to examine aviation safety oversight and the FAA's decision, a congressional aide said on Tuesday.

No timetable
While the NTSB and JTSB hunt for a solution to the battery question, there is also an open issue around fuel leaks on the Dreamliner. In early December, U.S. officials warned of a manufacturing fault with fuel lines, and earlier this month a JAL plane in Boston leaked before takeoff.

Industrial manufacturer Eaton Corp said Wednesday it was cooperating with investigators looking at the fuel leaks.

"Without speaking about either the incident or investigation, I can tell you that we do supply pumps and valves to the program," a spokeswoman said.

The 787 program was already years behind schedule before last week's grounding, which means Boeing cannot deliver newly manufactured planes to customers. Boeing's chief 787 engineer, Mike Sinnett, told an aviation conference in Dublin he could not say when that would change.

"I can't really say anything about the timeframe of the investigation. The NTSB is really the only authorized authority in the U.S. to talk about this investigation and they made some recent statements, but I can't speculate on timeframe," Sinnett said Wednesday in remarks made by phone from Seattle.

U.S. Transportation Secretary Ray LaHood, the country's top transportation official, said Wednesday the goal was to return the 787 to service as soon as possible but that the government would not rush the plane back either.

"We are working diligently with Boeing to figure out the problem and find a solution. Our goal is to get this done as quickly as possible, but we must be confident that the problems are solved before we can move forward," LaHood told the Aero Club of Washington, an aviation advocacy group.

FAA Administrator Michael Huerta, appearing at the same event, said the review was looking at the 787's certification, manufacturing and assembly processes, and that he could not speculate on an end date.

'Delayed so?many times'
For at least one Chinese customer, the uncertainty about the Dreamliner's production and delivery schedule has meant delays in launching new routes.

"Frankly, it's a little disappointing the aircraft has been delayed so many times," said Chen Feng, chairman of Hainan Airlines Co Ltd parent HNA Group, in an interview at the World Economic Forum in Davos. "We still think it's a good aircraft, but this has had some effect on our planning."

Hainan has 10 of the planes on order.

The grounding of the Dreamliner, an advanced carbon-composite plane with a list price of $207 million, has already forced Japan's ANA to cancel 151 domestic and 26 international flights scheduled for Jan. 23-28, affecting more than 21,000 passengers, the airline said on Monday.

ANA, which flies the most Dreamliners of any airline, is due to announce further flight cancellation plans on Thursday. The airline also said it may have to scale back its next two-year business plan because the 787 was to have been such a central part of that forecast.

Competition from Airbus
Boeing has already delivered 50 of the 787s to date. Around half of those have been in operation in Japan, but airlines in India, South America, Poland, Qatar and Ethiopia, as well as United Airlines in the United States, are also flying the plane.

Boeing's main competitor, EADS, said on Wednesday it did not expect the problems with the 787 to affect the certification of its own rival plane, the Airbus A350.

"We will do what is needed to avoid the same problems," EADS strategy chief Marwan Lahoud told France's Radio Classic.

Airbus has said it hopes to achieve the maiden flight of the carbon-composite A350 by the middle of this year. ?

Additional reporting by?Mari Saito and Yoko Kubota in Tokyo; Kelvin Soh in Davos; Elena Berton and Gilles Guillaume in Paris; Rhys Jones in London; Tim Hepher in Dublin; and Andrea Shalal-Esa and Jim Wolf in Washington.

Copyright 2013 Thomson Reuters.

Source: http://www.nbcnews.com/business/faa-no-timetable-returning-boeing-787s-skies-1C8088357

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Family of late Seau sues NFL

Rex Ryan, Woody JohnsonAP

The man who claims he had no role in the decision to trade for quarterback Tim Tebow is now reportedly pulling the strings on a trade for cornerback Darrelle Revis.

Jets owner Woody Johnson, who apparently doesn?t want to be perceived a meddler, definitely isn?t afraid to meddle.

Otherwise, Johnson wouldn?t want anything when it comes to Tebow, Revis, or any other player other than what the employees he has hired to handle football matters want.? If new G.M. John Idzik decides it makes sense to move Revis as he enters the final year of a contract that will void if Revis is on the roster the day after next year?s Super Bowl, then that?s what Woody should want.? If Idzik decides otherwise, that?s what Woody should want.

Are we still surprised they couldn?t give the job away?

A trade during the offseason won?t be easy.? Revis is recovering from a torn ACL.? There?s no way to know whether he?ll be the same guy that he was until he?s back on the field.? While Vikings running back Adrian Peterson was better than ever after an ACL tear, Ravens cornerback Domonique Foxworth never was the same again ? and ultimately retired.

If the goal is maximizing the return, the Jets should keep working Revis back to 100 percent, hope he comes back as good (or better) than ever, then dangle him before the trade deadline during the 2013 season to a contending team.? Of course, that approach could create an unwanted in-season distraction, especially if the Jets end up being better than expected next year.

The problem is that, now that the cat is reportedly out of the bag, Revis and his agents will look for clarity from the Jets.? And anyone who trades for him won?t want to give what the Jets will want without protection against Revis walking away next February.

Then there?s the cap hit.? While the Jets would avoid $6 million that is owed to Revis in 2013 ($3 million base salary, $1 million reporting bonus, $1 million roster bonus, $1 million workout bonus), they?ll carry a $3 million charge for his 2011 option bonus and absorb a $6 million cap acceleration if he is traded before June 1.

In other words, for a pre-June 1 trade, he?ll cost $9 million against the cap whether he?s on the team or not.

After June 1, the cap hit would drop to $3 million in 2013, with another $6 million applying to the cap in 2014.

There?s no easy solution to this one, especially now that the plans are supposedly known.? At least it will add some spice to Idzik?s introductory press conference, which has been scheduled for Thursday morning.

Maybe he?ll make like Rex and hop a plane to the Bahamas instead.? With an owner who seems to want to be the G.M., it would be hard to blame Idzik.

Source: http://profootballtalk.nbcsports.com/2013/01/23/seau-family-sues-nfl/related/

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